CD59 anticorps

N° du produit ABIN400702

Cet anticorps Souris Monoclonal détecte spécifiquement CD59 dans FACS et IHC (p). Il présente une réactivité envers Humain, Singe, Babouin et Chimpanzé.

Aperçu rapide pour CD59 anticorps (ABIN400702)

Antigène: CD59

Reactivité: Humain, Singe, Babouin, Chimpanzé

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD59 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: P282 (H19)

Détail du produit anti-CD59 anticorps

Specificité: Recognizes CD59 Glycoprotein.

Réactivité croisée (Details): Species reactivity (expected):Baboon, Chimpanzee and Monkey.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: MAC-inhibitory protein, Protectin, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MSK21,MACIF, MAC-IP, MIRL, HRF20, HRF-20, Membrane attack complex inhibition factor,Membrane inhibitor of reactive lysis, 20 kDa homologous restriction factor

Purification: Affinity Chromatography.

Immunogène: Full length protein corresponding to Human CD59.

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: 2 μg/IE6 cells. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD59

Antigène: CD59

Autre désignation: CD59

Sujet: CD59, an LY6 like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells. It is a potent inhibitor of the complement membrane attack complex action. It acts by binding to the C8 and/or C9 complements of the membrane attack complex, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is also involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.Synonyms: 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-IP, MAC-inhibitory protein, MACIF, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin

ID gène: 966

UniProt: P13987

Pathways: Système du Complément